Stem Cells in T1D

In this episode, Antonio Citro joins us to discuss bioengineering of a human iPSC-derived vascularized endocrine pancreas for type 1 diabetes.

In this episode, Jia Zhao discusses stem cell-derived islet models generated with a tunable differentiation strategy.

#asktheexpert #ATE #type1diabetes #t1d #t1dresearch #diabetesresearch #novel #diabetes #islet #isletmodels #tunabledifferentiation #stemmcell #stemcellmodel #modelsystem #diabetesmodel #diabetesmodelsystem

In this episode, Jeffrey Millman discusses identification of unique cell type responses in pancreatic islets to stress.

#asktheexpert #ATE #type1diabetes #t1d #t1dresearch #diabetesresearch #novel #diabetes #pancreaticislets #islets #isletstress #uniquecelltype #cells #pancreas

In this episode, Melissa Akguen discusses resolving human α versus β cell fate allocation for the generation of stem cell-derived islets.

#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #novel #alphacells #betacells #stemcells #stemcellmodel #islets #stemcellislets

In this episode, Eunike Setyono discusses generating future SC-islets product for islet replacement therapy.

#stemcells #SCislets #islettransplantation #isletreplacement #therapy #stemcelltherapy #asktheexpert #t1d ##novel #science #type1diabetes

In this episode, Xavier Gidrol & Emily Tubbs discuss promises and challenges in pancreatic organoid development.


#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #novel #pancreas #pancreaticorganoid #organoid #organoiddevlopment #stemcell #stemcellresearch

In this episode, Vikash Chandra discusses candidate genes to drug target for type 1 diabetes.

#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #drugs #drugtarget #drug #candidategenes #targett1d

In this episode, Hannah Pizzato discusses Engineering Human Pluripotent Stem Cells to Evade Immunological Rejection.

#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #pluripotent #humanpluripotent #engineering #protocol #immunologicalrejection #stemcells #pluripotentstemcells #evade

In this episode, Juan Dominguez, Fahd Qadir, Mayur Doke, & Isabella Altilio, a PhD student in the lab, join us to discuss pancreatic regeneration at work: lessons from dynamic scRNA sequencing of live human pancreas slices.

#cellmetabolism #scRNA #sequencing #RNAseq #singlecell #singlecellRNA #pancreas #pancreaticregeneration #regeneration #livehumanpancreas #humanpancreas #livehumanpancreasslices #pancreasslices #autoimmunity #novel #asktheexpert #ATE #T1D #type1diabetes #science

In this episode, Romina Bevacqua discusses CRISPR Gene Editing in Primary Human Islet Organoids.

#organoids #CRISPR #geneediting #crisprgeneediting #primaryhumanisletorganoids #humanislets #islets #pancreas #autoimmunity #novel #asktheexpert #ATE #T1D #type1diabetes #science

In this episode, Drs. Joe Qiao Zhou and Steve Xiaofeng Huang discuss their talk Restoring Glucose Homeostasis with Stomach-derived human insulin-secreting organoids.

#organoids #homeostasis #glucose #glucosecontrol #stemcells #stomach #insulinorganoids #type1diabetes #t1d #novel #science #asktheexpert #asktheexperts

Dr. Elad Sintov joins us from the Melton Lab at Harvard to discuss deciphering the immunogenicity of stem cell-derived islets and ways to dampen it.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Dr. Andrea Schietinger joins us to discuss an autoimmune stem-like CD8 T-cell population and how it drives T1D.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Dr. Dario Gerace joins us from the Melton Lab at Harvard to discuss engineering immune-evasive stem cell-derived islet cells.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Dr. Haiting Ma joins us to discuss a synthetic immune system and how it implicates beta-cell pyroptosis during T-cell mediated autoimmunity.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Dr. Maike Sander joins us to discuss building human stem cell models to study beta cell demise in T1D.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Dr. Nayara Leite joins us to discuss her work in stem cell science.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/