Indiana University SOM Site Visit

In this episode, Heba Ismail joins us to discuss the gut microbiome and metabolome in obesity and type 1 diabetes.

#type1diabetes #type1diabetesresearch #t1d #gutmicrobiome #gutmicrobiota #guthealth #obesity #metabolome #gutmetabolome #microbiome #research #microbiomeresearch

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In this episode, Andrew Templin joins us to discuss novel roles for RIP kinases in beta-cell cytotoxicity.

#type1diabetes #type1diabetesresearch #t1d #RIPkinases #kinases #betacell #betacellstress #betacellcytotoxicity

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In this episode, Erica Cai joins us to discuss genome-wide in vivo CRISPR screen uncovers ZBED3 as a transcriptional regulator of beta cell vulnerability in type 1 diabetes.


#type1diabetes #type1diabetesresearch #t1d #CRISPR #CRISPRscreen #betacell #betacellvulnerability #transcriptionalregulator #genomewidescreen #invivo #ZBED3

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In this episode, Jamie Felton joins us to discussing betting on the B team: a case for targeting B cells in type 1 diabetes progression.

#type1diabetes #type1diabetesresearch #t1d #Bcells #diseaseprogression #targetingbcells #diabetesprogression

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In this episode, Matthew Austin joins us to discuss dysfunctional beta-cell autophagy induces beta-cell stress and enhances islet immunogenicity.

#type1diabetes #type1diabetesresearch #immunogenicity #islet #betacell #betacellstress #autophagy #dysfunction #dysfunctionalbetacells #stress #t1d

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In this episode, Madeline McLaughlin joins us to discuss ultra-high resolution imaging enables quantification of beta cell ER.

#type1diabetes #type1diabetesresearch #imaging #highresolutionimaging #ultrahighresolution #quantification #betacell #betacellER #ER #endoplasmicreticulum #t1d

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In this episode, Chaitra Rao joins us to discuss the role of EV PD-L1 in Type 1 Diabetes Dynamics during the Indiana University site visit.

#type1diabetes #type1diabetesresearch #EV #extracellularvesicles #PDL1 #diabetesdynamics #t1d #tcells

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At this remote site visit with Indiana University SOM we discuss Type 1 Diabetes Moonshot at IU including discussions about pathology, biomarkers, and clinical translation.

#type1diabetes #type1diabetesresearch #mRNA #riskmarkers #riskscore #biomarkers #HLA #haplotypes #diabetesrisk #diabetesriskscore

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