Alpha Cells in T1D

In this episode, Irene Castellano PhD & Jakob Knudsen PhD join us to discuss Glucagon secretion by alpha-cells requires an intact tubulin-cytoskeleton-primary cilium axis.

In this episode, Eugenia Vazquez & Decio Eizirik join us to discuss Differential Immune & Apoptosis-Related Gene Signatures in Pancreatic Alpha & Beta Cells Contribute to their Fate in Type 1 Diabetes.

In this episode, Shani Peleg discusses RNA editing deficiency models differential immunogenicity of alpha and beta-cells.

In this episode, Danielle Dean joins us to discuss what makes an alpha cell an alpha cell and how we can use what we learn to treat type 1 diabetes.

#type1diabetes #t1d #TSS #sitevisit #asktheexpert #ATE #vanderbilt #vandy #VUMC #vanderbiltschoolofmedicine #alphacells #pancreas #betacells #islets #alpha

In this episode, Melissa Akguen discusses resolving human α versus β cell fate allocation for the generation of stem cell-derived islets.

#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #novel #alphacells #betacells #stemcells #stemcellmodel #islets #stemcellislets

In this episode, Elliott Brooks discusses KLF4 and NKX2.2 cooperate to regulate pancreatic alpha cells.

#novel #asktheexpert #ATE #T1D #diabetes #type1diabetes #human #science #novel #KLF4 #NKX2 #pancreas #alphacells #pancreaticalphacells #endocrine

Dr. Julia Panzer and Dr. Alejandro Caicedo join us to discuss the targeting of pancreatic alpha-cells to prevent hypoglycemia in T1D.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/

Ask the Expert: Dr. Mehdi Benkahla from the La Jolla Institute for Immunology takes us through HLA Class 1 Hyper-expression and pancreatic beta cells.

Ask the Expert is a ~30 minute digital cafe experience where scientists and grad students can meet and exchange with thought leaders in the field of type 1 diabetes. Link below to sign up for a seat in the cafe!

https://thesugarscience.org/ask-the-expert/