Staff Scientists, Immunology Discovery: Genentech

The department of Immunology Discovery conducts basic and translational research to enable new target discovery and preclinical drug development for inflammatory, autoimmune, fibrotic, and retinal disorders. We have access to unique resources including rich genetic, metagenomic, biomarker, and clinical outcome data from thousands of patients in interventional and observational clinical studies; state-of-the-art laboratory facilities; and dedicated collaborative support from core research functions including genetics, bioinformatics, pathology, in vitro and in vivo model systems, pharmacology, medicinal chemistry, antibody and protein engineering, structural biology, and proteomics.

We are seeking an outstanding established mid-career immunologist with a proven track record of leading original research as evidenced by significant conceptual and/or technical advances, high-profile publications, and mentorship of trainees.

Job Responsibilities

  • Direct a research lab investigating mechanisms of inflammatory human diseases such as (but not limited to) asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, idiopathic pulmonary fibrosis, systemic sclerosis, non-alcoholic steatohepatitis, type 1 diabetes mellitus, or inflammatory dermatoses.
  • Lead drug discovery teams from target identification through IND filing by working collaboratively with colleagues on assay development, in vivo animal models, pathology, bioinformatics, genetics, biomarker discovery, antibody engineering, small molecule drug discovery, pharmacology, and safety.
  • Mentor junior scientists and postdocs in Immunology department.
  • Maintain/build presence in external research community through publications and speaking engagements at conferences/academic institutions.
  • Develop and lead cross-functional research and target discovery strategies for inflammatory disorders.

Qualifications

  • PhD, MD, MD/PhD, or equivalent in immunology, inflammation, or related discipline
  • At least 5 years’ experience as a PI/lab head at major academic or industry research institution; associate to full professor or equivalent
  • Proven track record of highly cited publications in high-impact journals
  • National/international recognition as leader or emerging leader in immunology/inflammation
  • Experience managing/mentoring personnel (students, postdocs, technicians) as demonstrated by successful career advancement of trainees
  • Experience researching topics including but not limited to: cytokine signaling, myeloid cell biology, lymphocyte biology, cell death, immune cell trafficking, host-microbiome interactions, resolution of inflammation, mechanisms of autoimmunity, neuroinflammation, systems biology, and/or related disciplines.

Who We Are

Genentech, a member of the Roche group and founder of the biotechnology industry, is dedicated to pursuing groundbreaking science to discover and develop medicines for people with serious and life-threatening diseases. To solve the world’s most complex health challenges, we ask bigger questions that challenge our industry and the boundaries of science to transform society. Our transformational discoveries include the first targeted antibody for cancer and the first medicine for primary progressive multiple sclerosis.

Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We’re focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.

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