The Jackson Laboratory: Bar Harbor, Maine
This is an exciting opportunity to assume colony management responsibilities within the Serreze Lab. This position combines part-time mouse room colony management with part-time laboratory responsibilities. Part of this individual’s time will be spent on the maintenance of ~40 unique, mostly complex, mouse stocks used to delineate the genetic mechanisms of autoimmune type 1 diabetes. The remaining time will be spent performing laboratory activities such as reagent preparation, routine PCR- and flow cytometry-based genotyping, assisting in experiments, as well as performing other basic laboratory duties.
The Research Technologist/ Senior Research Technologist may be required to work flexible shifts that could include evenings, week-ends and/or holidays depending on the demands of the research and/or laboratory operations.
- Colony Management:
- Maintains appropriate breeding scheme(s) as required per strain.
- Reports colony productivity changes to Laboratory Manager and/or Supervisor.
- Consistently manages breeder rotation as required per strain and appropriately identifies and selects replacement breeder mice.
- Accurately maintains strain pedigree in JAX Colony Management computer software.
- Accurate urinary glucose analyses of large numbers of experimental mice to determine onset of autoimmune diabetes.
- Updates current colony status development notes citing appropriate milestone dates.
- Promptly utilizes genotyping results for colony maintenance.
- Implements the breeding scheme of new strains as determined by the Laboratory.
- Learns fundamental processes of data collection and analysis of reproductive performance.
- Experimental Support, Biomethods & Special Projects:
- Reagent preparation.
- Masters biomethod techniques and efficiently performs the following:
- Animal euthanasia in accordance with established laboratory procedures for humanely euthanizing mice in barrier facilities
- Animal restraint
- Ear notch, JAX Ear Tag, tattoo identification methods
- Tail tipping biosample collection
- Eye bleeding
- Tail vein i.v. injections
- Routine PCR and flow cytometry-based genotyping
- Assisting with experiments
- Harvesting tissues
- Research Technologist:
- Knowledge of mouse genetics as acquired by a Bachelors or Associate degree in the biological sciences OR 1–2 years of work experience in which animal husbandry and colony management and wet bench experience were major job responsibilities.
- Senior Research Technologist:
- Knowledge of mouse genetics as acquired by a Bachelors or Associate degree in the biological sciences AND 2+ years relevant experience; OR 5+ years of work experience in which animal husbandry, colony management were major job responsibilities
- Demonstrated ability to conduct experiments, interpret data and present finding.
- Demonstrated ability to deliver professional training materials.
- Successful completion of Lab Animal Science or equivalent experience.
- Biomethods training, or ability to quickly obtain such, resulting in the ability to ear notch mice, collect peripheral blood, tail tips, and cull mouse colonies.
- Prior training in PCR and/or flow cytometry based techniques is a plus.
- Successful completion of the Laboratory’s Genetics course or equivalent college accredited coursework.
- Skilled in utilizing the JAX Colony Management computer software system, or have the ability to quickly learn the Microsoft Access based software program.
- Knowledge of barrier room function.
- Detail orientated, flexible, ability to multi-task and remain focused.
- Excellent organizational skills and demonstrated ability to manage details accurately
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
The Jackson Laboratory’s 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!