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    • About
      • About us
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    • Tools
      • T1D Researchers Map
      • Data Research
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    Paper of the Week

    Large-scale genetic association and single cell accessible chromatin mapping defines cell type-specific mechanisms of type 1 diabetes risk

      https://www.biorxiv.org/content/10.1101/2021.01.13.426472v1  

    TSS admin January 16, 2021
    1 Comment

    Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics

    Spatial Multiplexing of Fluorescent Reporters for Imaging Signaling Network Dynamics Changyang Linghu 16 Shannon L. Johnson 16 Pablo A. Valdes Or A. Shemesh Won Min Park Demian…

    TSS admin January 9, 2021
    0 Comments

    Making trophoblasts (Dong et al)

    Derivation of trophoblast stem cells from naïve human pluripotent stem cells Chen Dong,  Mariana Beltcheva,  Paul Gontarz,  Bo Zhang,  Pooja Popli,  Laura A Fischer,  Shafqat…

    TSS admin December 17, 2020
    0 Comments

    Stem cells become cells with trophoblast qualities (Cinkornpumin et al)

    Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome Jessica K.Cinkornpumin1Sin YoungKwon1YixinGuo4IshtiaqueHossain1JacintheSirois12Colleen S.Russett1Hsin-WeiTseng1HiroakiOkae5TakahiroArima5Thomas F.Duchaine12WanluLiu3 William A.Pastor12 Stem Cell…

    TSS admin December 17, 2020
    0 Comments

    Hypoxia in places other than beta transplants (Soares et al)

    https://pubmed.ncbi.nlm.nih.gov/29105383/ Hypoxia and Placental Development Michael J Soares 1 2 3, Khursheed Iqbal 1, Keisuke Kozai 1 Affiliations 1Institute for Reproduction and Perinatal Research, Department of Pathology and Laboratory Medicine, University of…

    TSS admin December 16, 2020
    0 Comments

    How lncRNA works in nature’s implant, the placenta (Tongtong et al)

    Figure 4. PIWIL is essential for the invasion and proliferation of trophoblasts. LncRNA H19X is required for placenta development and angiogenesis through regulating a noncoding…

    TSS admin December 15, 2020
    0 Comments

    NKs at work in other implantation sites (Sojka et al)

    Uterine Natural Killer Cells Dorothy K. Sojka,* Liping Yang, and Wayne M. Yokoyama https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504766/

    TSS admin December 15, 2020
    0 Comments

    Testing islet cells with microelectrode array (Alassaf et al)

    Microelectrode Array based Functional Testing of Pancreatic Islet Cells Ahmad Alassaf 1 2 3, Matthew Ishahak 1 2, Annie Bowles 1 2, Ashutosh Agarwal 1 2 1Department of Biomedical Engineering, University of Miami, Coral Gables, FL 33146,…

    TSS admin December 11, 2020
    3 Comments

    Precision nanoparticles for drug delivery (Mitchell et al)

    NATURE REVIEWS: Engineering precision nanoparticles for drug delivery,Michael J. Mitchell 1,2,3,4,5 ✉, Margaret M. Billingsley1, Rebecca M. Haley 1, Marissa E. Wechsler6, Nicholas A. Peppas6,7,8,9,10 ✉ and Robert Langer https://mitchell-lab.seas.upenn.edu/wp-content/uploads/2020/12/s41573-020-0090-8.pdf  

    TSS admin December 10, 2020
    1 Comment

    “Feathering the nest” for islet transplant (Liu et al)

    A novel prevascularized tissue-engineered chamber as a site for allogeneic and xenogeneic islet transplantation to establish a bioartificial pancreas Yanzhuo Liu , Maozhu Yang , Yuanyuan Cui,…

    TSS admin December 9, 2020
    0 Comments
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