How do we progress from revolutionary bench science discoveries to clinically translatable therapeutics and techniques? In silico methods seek to leap over these foundational hurdles…
Planting the Seed By: James LeFevre and Neha Majety Embryonic stem cell treatment is a promising method of treating and potentially curing type 1 diabetes…
Gee whiz: HLA-G in placental development and pancreatic islet transplantation By: Shruthi Kandalai Islet cell transplantation, or transplanting insulin-producing islet cells from donors into patients,…
Shields Up: lessons from placental genetics to avoid immune attack on islet transplants By: Shruthi Kandalai Islet cell transplantation, or transplanting insulin-producing islet cells from…
stem cell therapy: current developments applied to t1d By: Alex Parrott and James LeFevre Stem cells are an incredibly useful and versatile tool to treat…
Born to be a “Natural Killer”: Understanding the Role of Natural Killer Cells and Galectins in Maternal Immune Response By: Neha Majety During pregnancy, a…
Protecting Transplanted Islets: Engineering Materials for Islet Tissue Transplantation By: Tiffany Richardson and Rachel Gurlin To mitigate the biological and lifestyle impacts of constant insulin…
Extracellular Vesicles and Islet Transplantation Strategies By: Zach Jones What is Islet Transplantation? Type 1 diabetes (T1D) is characterized by the autoimmune destruction of insulin-producing…
What Makes the Placenta So Tough? Placental Factors in Immunomodulation By: Hadeel Saab and Mari Yamamoto Immune checkpoint molecules (such as CTLA-4, TIM-3 and PD-1) work…
